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Abstract #4699

High resolution volumetric 3D-SoS MPRAGE detection of carotid intraplaque hemorrhage

J. Scott McNally1, Laura Eisenmenger1, Seong-Eun Kim1, Rock Hadley1, Adam De Havenon2, Jason Mendes1, Gerald Treiman3, and Dennis Parker1

1Radiology, University of Utah, Salt Lake City, UT, United States, 2Neurology, University of Utah, Salt Lake City, UT, United States, 3Surgery, Salt Lake City VA Medical Center

To provide a better method of detection and quantification of carotid intraplaque hemorrhage (IPH), we developed a motion-robust 3D radial stack of stars (SoS) MPRAGE sequence. 3D SoS MPRAGE outperformed 3D TOF in the detection and quantification of carotid IPH when compared with histology. The sequence was robust to motion and flow related artifacts. This sequence, when combined with high-SNR neck shape specific coils, can help identify stroke etiology, determine future stroke risk, and evaluate treatment response by quantifying IPH volume in future clinical trials aimed at decreasing carotid IPH.

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