To provide a better method of detection and quantification of carotid intraplaque hemorrhage (IPH), we developed a motion-robust 3D radial stack of stars (SoS) MPRAGE sequence. 3D SoS MPRAGE outperformed 3D TOF in the detection and quantification of carotid IPH when compared with histology. The sequence was robust to motion and flow related artifacts. This sequence, when combined with high-SNR neck shape specific coils, can help identify stroke etiology, determine future stroke risk, and evaluate treatment response by quantifying IPH volume in future clinical trials aimed at decreasing carotid IPH.
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