Abstract #4716

Accelerated Intracranial Vessel Wall Imaging using Compressed Sensing

Chengcheng Zhu¹, Bing Tian², Sinyeob Ahn³, Esther Raithel⁴, Gerhard Laub³, and David Saloner¹

¹Radiology, University of California, San Francisco, San Francisco, CA, United States, ²Radiology, Changhai Hospital, Shanghai, People's Republic of China, ³Siemens Healthcare, CA, United States, ⁴Siemens Healthcare, Erlangen, Germany

Current 3D black-blood high-resolution MRI (0.4-0.6mm isotropic) of intracranial vessel wall is limited by long scan times (~10 minutes). This study implemented a compressed sensing SPACE (CS-SPACE) sequence to reduce the scan time. The scan and reconstruction parameters were optimized in volunteers and then validated in patients. The optimized CS-SPACE protocol achieved good image quality and reliable vessel area measurements compared with SPACE, with a 37% time reduction. 0.5mm isotropic resolution can be achieved in <7 minutes, and 0.6mm³ is possible in 4 minutes. This fast intracranial vessel wall technique has potential for use in a clinical setting.

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