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Abstract #4716

Accelerated Intracranial Vessel Wall Imaging using Compressed Sensing

Chengcheng Zhu1, Bing Tian2, Sinyeob Ahn3, Esther Raithel4, Gerhard Laub3, and David Saloner1

1Radiology, University of California, San Francisco, San Francisco, CA, United States, 2Radiology, Changhai Hospital, Shanghai, People's Republic of China, 3Siemens Healthcare, CA, United States, 4Siemens Healthcare, Erlangen, Germany

Current 3D black-blood high-resolution MRI (0.4-0.6mm isotropic) of intracranial vessel wall is limited by long scan times (~10 minutes). This study implemented a compressed sensing SPACE (CS-SPACE) sequence to reduce the scan time. The scan and reconstruction parameters were optimized in volunteers and then validated in patients. The optimized CS-SPACE protocol achieved good image quality and reliable vessel area measurements compared with SPACE, with a 37% time reduction. 0.5mm isotropic resolution can be achieved in <7 minutes, and 0.6mm3 is possible in 4 minutes. This fast intracranial vessel wall technique has potential for use in a clinical setting.

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