Abstract #4734

Superior sagittal sinus venous oxygen saturation based on fully automated MR susceptometry : effects of slice dependent even-odd echo discrepancy and vascular angle correction

Chou-Ming Cheng^1,2, Tzu-Chen Yeh^3,4, Jen-Chuen Hsieh^2,4, and Hsiao-Wen Chung¹

¹Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, ²Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ³Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, ⁴Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan

Venous oxygen saturation (SvO₂) for estimation of global cerebral metabolic rate of oxygen is measured using MR susceptometry from the phase information obtained with multi-echo gradient-echo imaging. Automatic selection and segmentation of the superior sagittal sinus is performed with slice dependent even-odd discrepancy to avoid operator dependency. Results from 12 healthy subjects suggested that phase values of the vessel showing minimal even-odd echo discrepancy could be used as a useful information guiding selection of the appropriate vessel segment for SvO₂ estimations by taking into consideration the three dimensional vasculature.

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