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Abstract #4734

Superior sagittal sinus venous oxygen saturation based on fully automated MR susceptometry : effects of slice dependent even-odd echo discrepancy and vascular angle correction

Chou-Ming Cheng1,2, Tzu-Chen Yeh3,4, Jen-Chuen Hsieh2,4, and Hsiao-Wen Chung1

1Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 2Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, 3Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, 4Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan

Venous oxygen saturation (SvO2) for estimation of global cerebral metabolic rate of oxygen is measured using MR susceptometry from the phase information obtained with multi-echo gradient-echo imaging. Automatic selection and segmentation of the superior sagittal sinus is performed with slice dependent even-odd discrepancy to avoid operator dependency. Results from 12 healthy subjects suggested that phase values of the vessel showing minimal even-odd echo discrepancy could be used as a useful information guiding selection of the appropriate vessel segment for SvO2 estimations by taking into consideration the three dimensional vasculature.

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