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Abstract #4770

Regularized Curve Fitting Improves T1 Bias in Cardiac T2 Mapping

Galen D Reed1, Kenneth O Johnson1, Michelle M Nystrom1, Okai Addy1, Reeve Ingle1, Bob Hu1, Juan Santos1, and William Overall1

1HeartVista, Los Altos, CA, United States

Bias error is studied in T2-prepared single shot SSFP cardiac T2 mapping. Phantom experiments showed that although centric phase encode ordering reduces bias from T1 relaxation during single shot readouts, a residual bias of approximately 20% remains in the 1000 ms T1 regime. A regularized, three parameter exponential fitting model reduces this bias and generates T2 maps with low variance using 4 echo times.

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