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Abstract #4780

Diffusion-Kurtosis imaging predicts tumor upgrading in biopsy-proven Gleason score = 6 prostate cancers

Chen-Jiang Wu1, Yu-Dong Zhang1, and Hai-Bin Shi1

1Department of Radiology, the First Affiliated Hospital with Nanjing Medical University, Nanjing,China, People's Republic of China

The study investigated the feasibility of Diffusion Kurtosis Imaging (DKI) in predicting surgical result upgrading of biopsy-proven Gleason Score (GS) = 6 prostate cancer. The predicting efficiency of clinical variables (tumor volume, PSA level) and MRI variables (ADC, Dapp, Kapp) were compared by ROC analysis. DKI was found feasible to predict surgical result upgrading of biopsy-proven GS = 6 prostate cancer and Dapp-minimun had the highest Az value.

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