Abstract #4799

3T Restriction Spectrum Imaging Association with Prostate Cancer Gleason Score, PI-RADS v2 Score and Tumor Diameter on Whole Mount 3D-Mold-Sectioned Histopathology

Pooria Khoshnoodi¹, Sepideh Shakeri¹, Ashkan Shademan¹, Naznin Asvadi¹, Leila Mostafavi¹, Nathan White², David S. Karow², Daniel Margolis³, Anthony Sisk⁴, Robert Reiter⁵, and Steven Raman¹

¹Radiological Sciences, UCLA, Los Angeles, CA, United States, ²Radiological Sciences, UCSD, La Jolla, CA, United States, ³Radiology, Cornell University, New York, NY, United States, ⁴Pathology, UCLA, Los Angeles, CA, United States, ⁵Urology, UCLA, Los Angeles, CA, United States

Multiparametric MRI is becoming a crucial imaging for prostate cancers. A novel advanced, diffusion-based technique, restriction spectrum imaging (RSI) has been applied for prostate cancer imaging recently. In this work we will investigate the RSI performance in prostate cancer evaluation verified by post-surgery whole mount histopathology slides.

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