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Abstract #4800

DECIDE: Diffusion-rElaxation Combined Imaging for Detailed Placental Evaluation

Andrew Melbourne1, Rosalind Pratt1,2, David Owen1, Magdalena Sokolska3, Alan Bainbridge3, David Atkinson4, Giles Kendall2, Jan Deprest5, Tom Vercauteren1, Anna David2, and Sebastien Ourselin1

1University College London, London, United Kingdom, 2Institute for Women's Health, University College Hospital, London, United Kingdom, 3Medical Physics, University College Hospital, London, United Kingdom, 4Centre for Medical Imaging, University College Hospital, London, United Kingdom, 5UZ Leuven

We propose a new multi-compartment model for the tissue signal in MRI and apply this to images of liver and placenta. Motivated by different flow characteristics in these organs, a three compartment model comprising fast and slowly circulating fluid pools and a tissue pool is fitted to overlapping multi-echo T2 relaxometry and an intra-voxel incoherent motion diffusion acquisition with low b-values. We compare and contrast parametric maps for regions of interest in liver and placenta.

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