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Abstract #4811

4D Flow MRI in the Rhesus Macaque Fetus

Jacob Macdonald1, Philip Corrado1, Sydney Nguyen2, Kevin M Johnson1,3, Christopher J Francois3, Ian Bird2, Dinesh Shah4, Thaddeus G Golos2,4,5, and Oliver Wieben1,3

1Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, 2Comparative Biosciences, University of Wisconsin - Madison, Madison, WI, United States, 3Radiology, University of Wisconsin - Madison, Madison, WI, United States, 4Obstetrics and Gynecology, University of Wisconsin - Madison, Madison, WI, United States, 5Wisconsin National Primate Research Center, University of Wisconsin - Madison, Madison, WI, United States

4D flow measurements were performed with PC-VIPR in rhesus macaque monkeys undergoing healthy pregnancies to determine the feasibility of flow measurements in the fetal vasculature and umbilical cord. Flow measures appeared to be viable for the larger fetal vessels (aorta and IVC), but more variable in smaller vessels with slower flow (umbilical vessels). Image quality improved for later gestational ages as a result of increased vessel area.

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