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Abstract #4847

Hepatocellular carcinoma (HCC) screening with contrast-enhanced liver MRI: View-sharing artifact reduction with retrospective compressed sensing reconstruction

Paul Benjamin Stoddard1, Evan Levine2, Stephanie T. Chang3, Qiong Song1, Michael C. Muelly1, Brian A. Hargreaves2, Shreyas S. Vasanawala1, and Andreas M. Loening1

1Radiology, Stanford University, Stanford, CA, United States, 2Electrical Engineering and Radiology, Stanford University, Stanford, CA, United States, 3Radiology, Veteran Affairs Palo Alto Health Care System

Hepatocellular carcinoma (HCC) screening is a common indication for contrast-enhanced liver MRI. Dynamic contrast-enhanced (DCE) acquisitions often utilize view-sharing (VS) to optimize spatiotemporal resolution, but MRI can often be degraded by respiratory motion. VS introduces temporal blurring of high spatial frequencies that propagate coherent motion artifacts across phases. Compressed sensing (CS) can reduce the need for VS by recovering missing k-space data from pseudo-random undersampling, thus potentially reducing temporal blurring while maintaining spatial resolution. CS results in greatly reduced ghosting artifacts despite a more synthetic appearance.

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