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Abstract #4923

High Resolution Breast Diffusion Weighted Imaging Using 2-D Navigated Multishot SENSE EPI with Image Reconstruction using Image-Space Sampling Function (IRIS) at 3 T

Habib Rahbar1, Averi E Kitsch1, Hans Peeters2, Adrienne Kim1, Tyson Nunn3, and Savannah C Partridge1

1Radiology, University of Washington, Seattle, WA, United States, 2Body/Oncology, Philips Healthcare, Best, Netherlands, 3Radiology, Seattle Cancer Care Alliance, Seattle, WA, United States

Conventional diffusion weighted (DW) MRI relies on a single-shot (SS) echo planar imaging (EPI) acquisition, which suffers from limited spatial resolution and detrimental geometric distortions. Multishot (MS) EPI techniques hold potential to improve the image quality and spatial resolution of DW MRI. We tested the feasibility and performance for breast imaging of a recently developed DW MS-EPI sequence incorporating a novel IRIS image reconstruction approach. Our initial results demonstrate this DW MS-EPI technique to provide robust high resolution breast DW images, with good image quality and reduced geometric distortion compared to conventional DW SS-EPI.

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