Early enhancement heterogeneity and density on ultrafast bilateral DCE-MRI may differentiate benign and malignant breast lesions

Heterogeneity of enhancement has been shown to be a marker for malignancy in breast DCE-MRI, however standard dynamic protocols typically have low temporal resolution (60 to 90 seconds). Fast protocols have the advantage of accurately measuring early lesion kinetics. Heterogeneity of lesion enhancement in the first time-point (6 to 9 seconds) after arterial enhancement in the breast differed significantly between malignant and benign lesions; differences were not significant at later time-points.