Abstract #4921

Effect of menstrual cycle on background parenchymal enhancement and the detectability of breast cancer by contrast-enhanced breast MRI: a multicenter study of an Asian population

Takeshi Kamitani¹, Hidetake Yabuuchi², Mitsuhiro Tozaki³, Yoshihide Kanemaki⁴, Satoshi Kawanami⁵, Koji Sagiyama¹, Yuzo Yamasaki¹, Seitaro Shin¹, and Hiroshi Honda¹

¹Department of Clinical Radiology, Kyushu University, Fukuoka, Japan, ²Department of Health Sciences, Kyushu University, Fukuoka, Japan, ³Department of Radiology, Sagara Hospital Affiliated Breast Center, Kagoshima, Japan, ⁴Breast and Imaging Center, St. Marianna University School of Medicine, Kawasaki, Japan, ⁵Department of Molecular Imaging & Diagnosis, Kyushu Universtiy, Fukuoka, Japan

Background parenchymal enhancement (BPE) on breast contrast MRI is known to be associated with the menstrual cycle. We conducted a multicenter study to evaluate the effect of the menstrual cycle on BPE and cancer detectability by contrast-enhanced breast MRI in an Asian population. The Degrees of BPE and cancer detectability were assessed quantitatively and qualitatively. BPE were strongest in the proliferative phase. The detectability of breast cancer was better at the menstrual and proliferative phases than at secretary phase. Not only the proliferative phase but also the menstrual phase is suitable for breast MRI examinations of premenopausal Asian women.

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