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Abstract #4920

Breast Cancer and Body Adiposity by Breast MRI

Wenlian Zhu1 and Dmitri Artemov1,2

1Division of Cancer Imaging Research, Department of Radiology, The Johns Hopkins University School of Medicine, BALTIMORE, MD, United States, 2Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine

Using the thickness of the upper abdominal adipose layer measured from breast MRI as a surrogate body adiposity marker, this retrospective investigation validated a positive correlation between breast cancer and body adiposity in a cohort of 1616 breast MRI patients. Additionally, triple negative breast cancer was significantly associated with a younger age and higher body adiposity with respect to the hormone receptor positive breast cancer, while the hormone and HER-2 receptor positive (triple positive) type is only associated with a younger age. A trend of low body adiposity was observed in DCIS patients in the 30 – 49 age range.

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