Abstract #4920

Breast Cancer and Body Adiposity by Breast MRI

Wenlian Zhu¹ and Dmitri Artemov^1,2

¹Division of Cancer Imaging Research, Department of Radiology, The Johns Hopkins University School of Medicine, BALTIMORE, MD, United States, ²Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine

Using the thickness of the upper abdominal adipose layer measured from breast MRI as a surrogate body adiposity marker, this retrospective investigation validated a positive correlation between breast cancer and body adiposity in a cohort of 1616 breast MRI patients. Additionally, triple negative breast cancer was significantly associated with a younger age and higher body adiposity with respect to the hormone receptor positive breast cancer, while the hormone and HER-2 receptor positive (triple positive) type is only associated with a younger age. A trend of low body adiposity was observed in DCIS patients in the 30 – 49 age range.

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