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Abstract #4934

Ultrafast Dynamic Contrast Enhanced MRI of the Breast Using Compressed Sensing: A Novel Technique for Separate Visualization of Breast Arteries and Veins in Very Early Phase

Natsuko Onishi1, Masako Kataoka1, Shotaro Kanao1, Hajime Sagawa2, Mami Iima1, Rena Sakaguchi1, Akane Ohashi1, Ayami Ohno Kishimoto1, Marcel Dominik Nickel3, Masakazu Toi4, and Kaori Togashi1

1Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2Division of Clinical Radiology Service, Kyoto University Hospital, Kyoto, Japan, 3MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, 4Department of Breast Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

Ultrafast dynamic contrast enhanced (UF-DCE) MRI using compressed sensing enabled very fast scanning of the breast (every 3.7 sec/frame), and separately visualized breast arteries and veins. Breasts with cancers showed significantly shorter time intervals between arterial and venous visualization than the contralateral breasts without cancers. The time intervals in the breast with cancers tended to be shorter than those in the breasts with benign lesions. Shorter time intervals in breasts with cancers may reflect higher vascularity in malignancy. UF-DCE MRI has a potential to enable the differentiation of breast cancers in very early phase (0-60sec after contrast injection).

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