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Abstract #4938

Enabling high resolution MRE images of the breast

Stefan Heinz Hoelzl1, Sweta Sethi2, Jelizaveta Sudakova1, Ayse Sila Dokumaci1, Jurgen Henk Runge1, Tony Ng3, Arnie Purushotham4, and Ralph Sinkus1

1Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom, 2Department of Research Oncology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom, 3Division of Cancer Studies, King's College London, London, United Kingdom, 4Department of Imaging Chemistry and Biology, King's College London, London, United Kingdom

Achieving high-resolution MR-Elastography images of the breast is a challenge due to shear wave attenuation and shadowing effects in breast tissue resulting in loss of wave energy and hence poor signal to noise ratio. We present a novel breast transducer set-up to ensure complete wave penetration throughout the entire breast. Waves reach even far upwards to enable quantification of axillary lymph nodes. Mechanical vibrations are generated via a novel concept utilizing an eccentric rotor that yields inherently constant amplitude with driving frequency. Volunteer results of wave speed and attenuation at 2mm isotropic resolution are presented including the axilla region.

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