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Abstract #4968

Feasibility of Performing Dynamic and Delayed Enhancement and Magnetization Transfer Ratios in pediatric patients undergoing clinically-indicated MRE: pilot study to assess image quality for quantitative evaluation

Mary-Louise Catherine Greer1,2, Susan Shelmerdine3, Kedar Patil1,2, Claire Cuscaden4, Debra Drossman1, and Logi Vidarsson1

1Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada, 2Department of Medical Imaging, University of Toronto, Toronto, ON, Canada, 3Department of Radiology, Great Ormond Street Hospital, London, United Kingdom, 4Department of Radiology, The Royal Brisbane and Women's Hospital, Brisbane, Australia

Purpose: Assess feasibility of applying magnetization transfer (MT) and dynamic and delayed enhancement (DCE) sequences during MR Enterography(MRE) in children.

Methods: REB approved, in this prospective study, patients =/< 18 years undergoing MRE for suspected or proven inflammatory bowel disease were consented for application of MT and DCE sequenced in addition to standard clinical sequences. These were assessed and prospectively recruited and imaging sequences applied. Imaging was subjectively analysed by two radiologists or a radiologists and physicist in the first arm by consensus for sequence modification.

Results: Inter and intra-reader analysis was undertaken.

Conclusion: DCE is robust, MTR requires further modification.

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