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Abstract #4989

Chemical Shift Effect Predicting Lymph Node Status in Rectal Cancer using High-Resolution MR Imaging with Node-for-node Matched Histopathological Validation

chongda zhang1, hongmei zhang1, feng ye1, yuan liu1, and chunwu zhou1

1Department of Diagnostic Radiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China

To evaluate the value of chemical shift effect (CSE), as well as other criteria for the prediction of lymph node status. Lymph nodes harvested from transversely whole-mount specimens were compared with in vivo and ex vivo images to obtain MR characteristics including CSE, as well as other predictors of 255 benign and 35 metastatic nodes. Our results revealed that CSE is a reliable predictor for differentiating benign from metastatic lymph nodes. Other predictors of nodal location, border, signal intensity and minimum distance to rectal wall were also proved to be useful for the diagnosis.

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