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Abstract #5011

T2-weighted Dixon TSE for accelerated simultaneous grading of whole body skeletal muscle fat infiltration and edema in patients with neuromuscular diseases

Sarah Schlaeger1, Elisabeth Klupp1, Dominik Weidlich2, Barbara Cervantes2, Marcus Deschauer3, Benedikt Schoser4, Sarah Bublitz3, Federica Montagnese4, Christoph Katemann5, Hendrik Kooijman5, Ernst J. Rummeny2, Claus Zimmer1, Jan S. Kirschke1, and Dimitrios C. Karampinos2

1Department of Diagnostic and Interventional Neuroradiology, Technical University of Munich, Munich, Germany, 2Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, 3Department of Neurology, Technical University of Munich, Munich, Germany, 4Friedrich-Baur-Institut, Ludwig-Maximilians-University, Munich, Germany, 5Philips Healthcare, Hamburg, Germany

The assessment of fatty infiltration and edema in the whole body musculature of patients with neuromuscular diseases typically requires the separate performance of a T1-weighted sequence and a fat suppressed T2-weighted sequence. T2-weighted Dixon TSE enables the generation of T2-weighted fat-separated and water-separated images, which could be used to simultaneously assess fatty infiltration and edema and to reduce total scan time. The present study examines the diagnostic performance of whole body T2-weigthed Dixon TSE imaging in 10 patients with neuromuscular diseases.

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