In general, it is difficult to obtain functional information about water and lipid in tissues at the same time. We, therefore, developed a novel method using chemical shift displacement and recovery-based separation of lipid tissue (SPLIT) with different inversion times, echo times, and b-values to simultaneously acquire diffusion, perfusion, T1, T2, and lipid fraction in the calf. All parameters obtained with the SPLIT were consistent with previously reported values. This method enables simultaneous acquisition of functional information without special pulse sequence.
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