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Abstract #5032

Chemical Shift Displacement and Recovery-based Simultaneous Water and Lipid Imaging for Quantitative Multiparametric MRI

Naoki Ohno1, Tosiaki Miyati1, Shuto Suzuki1, Hirohito Kan2, Toshitaka Aoki2, Yoshitaka Nakamura1, Yuki Hiramatsu1, and Toshifumi Gabata3

1Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, 2Department of Central Radiology, Nagoya City University Hospital, Nagoya, Japan, 3Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan

In general, it is difficult to obtain functional information about water and lipid in tissues at the same time. We, therefore, developed a novel method using chemical shift displacement and recovery-based separation of lipid tissue (SPLIT) with different inversion times, echo times, and b-values to simultaneously acquire diffusion, perfusion, T1, T2, and lipid fraction in the calf. All parameters obtained with the SPLIT were consistent with previously reported values. This method enables simultaneous acquisition of functional information without special pulse sequence.

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