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Abstract #5086

Revisiting the experimental base of compositional biomarkers: A meta-analysis study

Jose G Raya1, Amparo Ruiz1, and Uran Ferizi1

1Department of Radiology, New York University School of Medicine, New York, NY, United States

We aim to perform a meta-analysis of the corpus of experimental results accumulated for compositional MRI biomarkers of articular cartilage used in clinical studies. We summarized the data according to the statistical evidence that is reported. We report the correlation of MRI parameters with composition, the ability of MRI parameters to detect group differences between healthy and degraded cartilage, and the ability of MRI to detect cartilage damage.

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