Abstract #5087

Changes in collagen and proteoglycan in cartilage with OA severity

Jose G Raya¹, Uran Ferizi¹, Amparo Ruiz¹, Steven B Abramson², Jenny Bencardino¹, and Svetlana Krasnokutsky Samuels²

¹Department of Radiology, New York University School of Medicine, New York, NY, United States, ²Department of Medicine, New York University School of Medicine, New York, NY, United States

The objective of this work was to investigate differences in cartilage matrix composition and structure across subjects with different stages of OA severity and test if the changes in the collagen network are concomitant or subsequent to the changes in proteoglycan.

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