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Abstract #5088

Magnetic resonance imaging of the zone of calcified cartilage (ZCC) in the knee joint using 3D UTE Cones sequences

Yinghua Zhao1,2, Yajun Ma1, Michael Carl3, Xing Lu1, Yanchun zhu1, Eric Y Chang1,4, and Jiang Du1

1University of California, San Diego, San Diego, CA, United States, 2Radiology, Third Affiliated Hospital of Southern Medical University (Academy of Orthopedics ยท Guangdong Province), Guangzhou, People's Republic of China, 3GE Healthcare, San Diego, CA, United States, 4Radiology Service, VA San Diego Healthcare System, San Diego, CA, United States

The zone of calcified cartilage (ZCC) is a thin layer between articular cartilage and bone. The ZCC plays an important role in the pathogenesis of osteoarthritis (OA) but has never been imaged in vivo with magnetic resonance (MR) imaging techniques. In this study we aimed to investigate the feasibility of direct imaging of the ZCC in healthy volunteers using a three dimensional (3D) ultrashort echo time (UTE) Cones sequence on a clinical whole body 3T scanner.

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