This work examines the use of UTE-T2* profile analysis to assess sub-surface knee cartilage structural changes in 26 ACL-reconstructed subjects and compares UTE-T2* metrics to kinetic and kinematic measures of walking. UTE-T2* profile characteristics detect differences between ACL-reconstructed and uninjured knees. Side-to-side differences in an individual’s UTE-T2* profile metrics correlate with side-to-side differences in their gait metrics. The results suggest that UTE-T2* profile characteristics of cartilage are a useful metric for identifying cartilage subsurface changes early after ACLR and may reflect matrix changes resulting from altered loading.
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