Abstract #5098

Feasibility of GRASP DCE-MRI in children with Juvenile Idiopathic Arthritis (JIA)

Paul de Heer¹, Robert Hemke¹, Cristina Lavini¹, Jasper Schoormans², Bram F. Coolen², Anouk M. Barendregt¹, Gustav J. Strijkers², Mario Maas¹, Jaap Stoker¹, Aart J. Nederveen¹, and Jurgen H. Runge^1,3

¹Radiology, AMC, Amsterdam, Netherlands, ²Biomedical Engineering & Physics, AMC, Amsterdam, Netherlands, ³Division of Imaging Sciences and Biomedical Engineering, King’s College London, London, United Kingdom

Juvenile Idiopathic Arthritis (JIA) is the most common rheumatic disease in childhood and represents one of the leading causes of pediatric acquired disability. The aim of our study was to evaluate feasibility of high spatiotemporal resolution GRASP DCE-MRI in children with JIA and secondly to compare image quality between GRASP and conventional DCE-MRI in evaluating synovitis. In this pilot study, GRASP DCE-MRI proved to be feasible in a child with JIA. Moreover, for the evaluation of synovitis significantly higher spatial resolution and much cleaner signal-enhancement plots could be obtained using GRASP compared to conventional DCE-MRI.

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