Abstract #5126

Quantitative Lower Limb Perfusion Territory Imaging with Vessel Encoded Arterial Spin Labeling

Lian Ding¹, Fei Gao², Chengyan Wang¹, Wenjian Huang¹, Jue Zhang^1,2, Xiaoying Wang^1,3, and Jing Fang^1,2

¹Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China, ²College of Engineering, Peking University, Beijing, People's Republic of China, ³Department of Radiology, Peking University First Hospital, Beijing, People's Republic of China

Critical limb ischemia (CLI) represents the most severe clinical manifestation of peripheral arterial disease (PAD). It has been proved that l lower extremity arterial stenosis and collateral circulation compensatory ability after occlusion play an important role on CLI. This study proposed a strategy for assessment of lower extremity arterial stenosis and collateral circulation compensatory ability by the noninvasive vessel-encoded arterial spin labeling (VEASL) to quantitatively assess perfusion territory of lower extremity arterial. The lower limb perfusion territory image and the angiosome map were obtained in this study, indicating the potential of VEASL for CLI assessment.

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