Abstract #5207

T1 Mapping of NIST Phantom at 7T

Yi-Fen Yen¹, Kathryn E. Keenan², Karl F. Stupic², Andre van der Kouwe¹, and Jonathan R. Polimeni^1,3,4

¹Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ²Physical Measurement Laboratory, National Institute of Standards and Technology (NIST), Boulder, CO, United States, ³Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁴Department of Radiology, Harvard Medical School, Boston, MA, United States

We are reporting quantitative T1 values of the NIST T1 phantom at 7T for the first time by using IR-SE method. We also compared the accuracy of T1 mapping by using MP2RAGE and variable flip angle (VFA) methods against the IR-SE T1s at 7T and found MP2RAGE gave more accurate T1 measure than VFA, for T1 of 300 ms to 2000ms (the range of brain T1). Although the accuracy of MP2RAGE at 7T was not as good as that at 3T (also shown), MP2RAGE is a promising technique for accurate brain T1 mapping at 7T within a clinically acceptable scan time.

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