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Abstract #5213

An SNR analysis of DENSE at 7T vs 3T for the measurement of whole brain tissue pulsatility

Ayodeji L Adams1, Peter R Luijten1, and Jaco J.M Zwanenburg1

1Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands

Cardiac induced brain tissue pulsatility holds potential as a means to study the viscoelastic properties of the aging brain. In this study we measured the brain tissue motion in 8 healthy volunteers with DENSE at both 7T and 3T, and assessed the gain in SNR between field strengths. 4D SNR maps for both field strengths were made and examined with a robust histogram analysis. The mean SNR for all volunteers at 7T and 3T was 21.2 ± 6.3 and 7.1 ± 2.5 respectively. The higher SNR at 7T will likely yield greater accuracy in quantifying brain tissue pulsatility.

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