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Abstract #5214

Fluid and white matter suppression (FLAWS) with MP2RAGE sequence at 7T.

Yuta Urushibata1, Hideto Kuribayashi1, Junko Inoue1, Tobias Kober2,3,4, John Grinstead5, and Tomohisa Okada6

1Siemens Healthcare K.K., Tokyo, Japan, 2Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 3Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, 4LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 5Siemens Medical Solutions, Inc., United States, 6Kyoto University, Kyoto, Japan

Fluid and white matter suppression (FLAWS) is a technique to suppress cerebrospinal fluid (CSF) and white matter (WM) using the MP2RAGE sequence, which has been introduced for 3T. In this study, FLAWS was applied at 7T and compared to a SPACE double inversion recovery (DIR). Inversion times of the sequences were optimized for volunteer brain images at 7T. FLAWS showed better suppression of CSF and WM, more homogeneous gray matter (GM) delineation, as well as better GM/WM contrast compared with DIR.

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