Abstract #5215

High resolution PET insert for high field preclinical MRI: evaluation of single ring system using 7T field strength

Willy Gsell¹, Uwe Himmelreich¹, Cindy Casteels², Christophe M. Deroose², Antonio J. Gonzalez³, Albert Aguilar³, Carlos Correcher⁴, Emilio Gimenez⁴, Cesar Molinos⁴, Ramiro Polo⁴, Thorsten Greeb⁵, Ralph Wissmann⁵, Sven Junge⁵, and Jose M. Benlloch³

¹Biomedical MRI, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium, ²Nuclear Medicine, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium, ³i3M, Valencia, Spain, ⁴Oncovision, Valencia, Spain, ⁵Bruker Biospin, Ettlingen, Germany

We designed a novel PET insert based on monolithic LYSO crystals. From our first evaluation, we can conclude that sub-millimeter detector spatial resolution, combined with accurate photon DOI determination, make it possible to acquire high resolution reconstructed images. This enables us now to combine simultaneously high resolution and sensitivity PET with high field preclinical MRI to extract simultaneously complex data from anatomical to molecular information and to dynamically follow non-invasively animal models of different pathologies with no compromise in performance of each imaging modality.

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