Abstract #5218

Comparison of pCASL and FAIR for measuring Renal Blood Flow (RBF) of mouse kidney at 9.4T

Sankar Seramani¹, Lydiane Hirschler², Boominathan Ramasamy¹, Sakthivel Sekar¹, Kishore Bhakoo¹, Emmanuel Luc Barbier², and Kuan Jin Lee¹

¹Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore, Singapore, ²Université Grenoble Alpes, Grenoble Institut des Neurosciences, Grenoble, France

Arterial Spin Labeling (ASL) is a non-invasive MRI technique which can be used to measure quantitative renal perfusion without the injection of contrast agents. The goal of this study is to compare the performance of pCASL with FAIR in measuring Renal Blood Flow in mouse kidney at Ultra High Field (UHF) MR. Based on our experimental results, pCASL based perfusion measurement shows similar reproducibility when compared to FAIR method. pCASL shows better SNR sensitivity and lower in ROI variation of RBF in the kidney when compared to FAIR based ASL method at 9.4 Tesla.

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