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Abstract #5219

Spatial Resolution Analysis Comparing Density-Adapted and Conventional Projection Reconstruction in Chlorine-35 MRI at 9.4 T

Ruomin Hu1, Matthias Malzacher1, Mathias Davids1, Andreas Neubauer1, Simon Konstandin2, and Lothar R. Schad1

1Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany, 2MR-Imaging and Spectroscopy, Universty of Bremen, Bremen, Germany

35Cl MRI has been of interest for both human and animal in vivo applications to visualise chloride homeostatic changes. In this study we performed measurements of resolution phantoms at an isotropic resolution of 0.490 and 0.326 mm using scanner-equipped ultrashort echo time 3D (UTE3D) and newly implemented density-adapted 3D projection reconstruction (DA-3DPR) sequences with subsequent spatial resolution analysis. DA-3DPR images with visibly higher SNR are capable of resolving both gross and fine structures with more reliable signal distributions and more consistent rendition of structure shapes. Moreover, penalty-free radial oversampling leads to more extended artefact-free regions, allowing for smaller FOVs and reduced measurement times.

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