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Abstract #5224

3D FLAIR at 7T using Direct Signal Control

Arian Beqiri1, Hans Hoogduin2, Alessandro Sbrizzi2, Joseph V Hajnal1,3, and Shaihan J Malik1

1Biomedical Engineering and imaging Sciences, King's College London, London, United Kingdom, 2Image Sciences Institute, University Medical Centre Utrecht, Utrecht, Netherlands, 3Centre for the Developing Brain, King's College London, London, United Kingdom

3D-FLAIR imaging at 7T using a 3D Turbo Spin Echo (TSE) readout is a useful tool for assessment of neurological disorders. The method does however suffer from variation in signal homogeneity due to B1+ inhomogeneities making whole-brain coverage difficult.

In this work, image uniformity is improved by using Direct Signal Control (DSC). The DSC method uses predictions of echo amplitudes to compute optimized RF shims that vary on a pulse by pulse basis throughout the echo train with the aim of homogenising signal properties. Low signal in the centre of the brain and cerebellum is effectively recovered in multiple subjects.

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