Abstract #5242

The clinical relevance of correcting susceptibility-related distortions in presurgical fMRI at 7 T

Pedro Lima Cardoso¹, Barbara Dymerska¹, Beáta Bachratá¹, Florian Ph.S. Fischmeister^1,2, Nina Mahr^1,2, Eva Matt^1,2, Siegfried Trattnig¹, Roland Beisteiner^1,2, and Simon Daniel Robinson¹

¹High Field Magnetic Resonance Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²Study Group Clinical fMRI, Department of Neurology, Medical University of Vienna, Vienna, Austria

The clinical relevance of correcting susceptibility-related distortions using a recently-developed dynamic distortion correction (DDC) approach is assessed. This was applied in fMRI data acquired from a group of 12 patients with a range of neuropathologies at 7 T. Despite the presence of pathologies, time series of artifact-free field maps were generated. If distortion correction was neglected, substantial displacements, both in EPI geometry and activation, were observed. Two cases with potential clinical implications were identified. The DDC was able to accurately correct distortions in all cases and is shown to be effective and clinically relevant in presurgical planning at 7 T.

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