The clinical relevance of correcting susceptibility-related distortions using a recently-developed dynamic distortion correction (DDC) approach is assessed. This was applied in fMRI data acquired from a group of 12 patients with a range of neuropathologies at 7 T. Despite the presence of pathologies, time series of artifact-free field maps were generated. If distortion correction was neglected, substantial displacements, both in EPI geometry and activation, were observed. Two cases with potential clinical implications were identified. The DDC was able to accurately correct distortions in all cases and is shown to be effective and clinically relevant in presurgical planning at 7 T.