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Abstract #5267

Evaluation of two novel MRI techniques for the assessment of intracranial pulsatility

Bowen Fan1, Lirong Yan2, Kay Jann2, Mayank Jog2, Ying Kui3, and Danny JJ Wang2

1Department of Engineering Physics, Tsinghua University, Beijing, People's Republic of China, 2Laboratory of FMRI Technology, Mark & Mary Stevens Neuroimaging and Informatics Institute,Keck School of Medicine,University of Southern California, University of Southern California, CA, United States, 3Key Laboratory of Particle and Radiation Imaging, Ministry of Education, Medical Physics and Engineering Institute, Department of Engineering Physics, Tsinghua University, Beijing, People's Republic of China

The brain pulsatility plays an important role in various cerebral pathology, such as brain tumor and traumatic brain injury. Two MRI methods have been recently developed for assessing brain biomechanical features using a ECG-gated cine sequence with different processing strategies. In this study, we evaluated and compared the two methods. Consistent findings were obtained using both methods that the majority of cardiac-induced brain pulsatile motion occurs in the brain stem and basal ganglia as well as in big arteries.

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