Abstract #5274

THE IMPACT OF THE LOCAL, MESOSCOPIC FREQUENCY DISTRIBUTION AND DIFFUSION IN GRAY AND WHITE MATTER TO THE STATIC bSSFP SIGNAL PROFILE

Mario Gilberto Báez-Yánez^1,2, Philipp Ehses^1,3, and Klaus Scheffler^1,3

¹Department of High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, ²Graduate Training Centre of Neuroscience, University of Tuebingen, Tuebingen, Germany, ³Department of Biomedical Magnetic Resonance, University of Tuebingen, Germany

The phase accumulation that spins experience during a MR sequence is closely linked to the microstructure within the voxel, and basically produces changes in T2* or T2. The present abstract demonstrates how the static bSSFP signal profile is modified by the influence of local susceptibility differences produce by the underlying local-frequency distribution and diffusion effects related to white matter and gray matter at 9.4T. We apply an analytical presentation of the diffusion-modified frequency distribution, previously only used for gradient and spin echoes, to bSSFP and we prove the applicability of this theory to bSSFP by Monte Carlo simulations and measurements.

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