Abstract #5278

Shared and Specific Intrinsic Functional Connectivity Patterns in Unmedicated Bipolar Disorder and Major Depressive Disorder

Ying Wang¹, Junjing Wang², Yanbin Jia³, Tao Liu³, Yao Sun¹, Shuming Zhong³, Zhongping Zhang⁴, Li Huang¹, and Ruiwang Huang²

¹Medical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China, ²Center for the Study of Applied Psychology & MRI Center,Center, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, ³Department of Psychiatry, First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China, ⁴MR Research China, GE Healthcare, Beijing

Our findings suggest that bipolar disorder (BD) and major depressive disorder (MDD) may have some shared and morespecific impairments of functional connectivity patterns during the depressiveperiod, providing new evidence for pathophysiology of BD and MDD at thelarge-scale whole brain connectivity level.

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