Motion dominates the contribution to variance in fMRI time series and it is therefore important to account for this variability correctly. Currently, most correction schemes use a rigid body realignment procedure, but interactions with magnetic field inhomogeneities and physiological fluctuations lead to non-linear deformations. Non-linear realignment increased spatial resolution by harvesting sub-voxel shift information with little impact on tSNR. Activated regions showed a better delineation with a clear match to anatomical features. Importantly, our proposed method can be applied to already acquired fMRI data sets to improve spatial conspicuity.
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