Abstract #5385

Effects of tCDS to vmPFC functional connectivity after 36 hours total sleep deprivation: a resting-state fMRI study

Li Jiyuan¹, Song Yunlong¹, Shao Yongcong², Pan Zhibin¹, Wu Yao¹, and Zhou Lu²

¹CT and MRI, The General Hospital of The Air Force People's Liberation Army, Beijing, People's Republic of China, ²Cognitive and Mental Health Research Center, Beijing Institute of Basic Medical Sciences, Beijing, People's Republic of China

There are fifteen health indibiduals recruited in order To explore the changes of functional connectivity in vmPFC with tDCS stimuli after 36 hours sleep deprivation. Colleceting resting-state fMRI data under the tDCS stimuli and sham stimuli conditions. Using the vmPFC as the seed region,and then the time courses of all brain voxels were correlated separately with the mean time course generated from the ROI by Pearson cross-correlation. Finally, we found that tDCS can effectively mediate the dysfunction of brain connectivity.

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