Abstract #5390

Topological Networks reorganization in two profile of High Potential Children: a resting state fMRI study.

Ilaria Suprano¹, Chantal Delon-Martin, Gabriel Kocevar, Claudio Stamile, Salem Hannoun , Pierre Fourneret, Olivier Revol, Fanny Nusbaum, and Dominique Sappey-Marinier

¹Université Claude Bernard - Lyon 1, Lyon, France

High Potential Children diagnosis remains unclear. We proposed to examine 56 children with a resting state fMRI study. The profile of network topology was explored in two different groups of HP estimating the hub disruption index (k). A disruption of the order of importance of specific nodes in both the HP groups was found with a stronger reorganization in heterogeneous group. This results may offer a confirm of the different psychiatric characteristics that exist between the HP profiles. The sensitivity of graph metrics based on rs-fMRI was demonstrated to be very helpful to provide a better characterization of HP children.

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