To assess the impact of repetition time (TR) and window size on the temporal features of BOLD functional connectivity (FC) using a sliding window approach in event-related fMRI. in addition, test the feasibility of this approach in epilepsy. We calculated the functional connectivity degree (FCD) by counting the total number of connections of a given voxel above a predefined threshold based on Pearson correlation. In summary, we showed that dynamic FCD transients are better detectable with sub-second TR than conventional TR, indicating a potential to study the temporal characteristics of interictal epileptiform discharges and seizures in epilepsy patients.
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