Abstract #5400

Comparison of fMRI and MEG language localization tasks—a prospective study of noninvasive presurgical functional mapping

Li Zheng¹, Jingwei Sheng¹, Tianyi Qian², Thomas Beck³, and Jia-hong Gao¹

¹Center for MRI Research, Peking University, Beijing, People's Republic of China, ²Siemens Healthcare, MR Collaborations NE Asia, Beijing, People's Republic of China, ³Siemens Healthcare, Application Development, Erlangen, Germany

In patients with intractable epilepsy, anomalous cortical organization could be observed and pre-surgical planning involving the localization of cortical language areas is critical. As a prospective study, we compared language localization using functional magnetic resonance imaging (fMRI) and magnetoencephalography (MEG) with advanced source estimate method in 18 volunteers. Group analysis results showed something similar or discordant between fMRI and MEG activation. It is consider that fMRI technique combined MEG can used for the preoperative localization and postoperative functional evaluation in the future.

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