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Abstract #5400

Comparison of fMRI and MEG language localization tasks—a prospective study of noninvasive presurgical functional mapping

Li Zheng1, Jingwei Sheng1, Tianyi Qian2, Thomas Beck3, and Jia-hong Gao1

1Center for MRI Research, Peking University, Beijing, People's Republic of China, 2Siemens Healthcare, MR Collaborations NE Asia, Beijing, People's Republic of China, 3Siemens Healthcare, Application Development, Erlangen, Germany

In patients with intractable epilepsy, anomalous cortical organization could be observed and pre-surgical planning involving the localization of cortical language areas is critical. As a prospective study, we compared language localization using functional magnetic resonance imaging (fMRI) and magnetoencephalography (MEG) with advanced source estimate method in 18 volunteers. Group analysis results showed something similar or discordant between fMRI and MEG activation. It is consider that fMRI technique combined MEG can used for the preoperative localization and postoperative functional evaluation in the future.

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