Abstract #5416

Mapping TMS immediate effects by concurrent TMS/fMRI using a dedicated high-sensitivity coil array

Martin Tik¹, Michael Woletz¹, Lucia Navarro de Lara¹, Ronald Sladky¹, André Hoffmann¹, Allan Hummer¹, Nicole Geissberger¹, and Christian Windischberger¹

¹Division MR Physics, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Wien, Austria

In this work we show the feasibility of a novel concurrent TMS/fMRI setup based on two multi-channel receive arrays that allows for whole brain fMRI data acquisition during brain stimulation. We show that stimulation at frequencies of 1 and 10Hz, respectively, leads to distinct changes in BOLD signal. We also report increased TMS-related network effects with higher stimulation. This validity check sets the frame for efficacy studies investigating the TMS stimulation of cortical areas for modulating complex brain networks.

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