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Abstract #5416

Mapping TMS immediate effects by concurrent TMS/fMRI using a dedicated high-sensitivity coil array

Martin Tik1, Michael Woletz1, Lucia Navarro de Lara1, Ronald Sladky1, André Hoffmann1, Allan Hummer1, Nicole Geissberger1, and Christian Windischberger1

1Division MR Physics, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Wien, Austria

In this work we show the feasibility of a novel concurrent TMS/fMRI setup based on two multi-channel receive arrays that allows for whole brain fMRI data acquisition during brain stimulation. We show that stimulation at frequencies of 1 and 10Hz, respectively, leads to distinct changes in BOLD signal. We also report increased TMS-related network effects with higher stimulation. This validity check sets the frame for efficacy studies investigating the TMS stimulation of cortical areas for modulating complex brain networks.

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