Real-time damage estimates provided by Magnetic Resonance Temperature Imaging (MRTI) and appropriate thermal dose models can provide crucial feedback during of thermal ablation procedures. However, these models are not tailored to the post-treatment radiological endpoints that are used to verify the extent of the thermal lesion after therapy. A technique is developed to allow estimation of thermal dose model parameters through retrospective analysis of MRTI and post-treatment imaging. The feasibility of this technique is investigated in a protein coagulation phantom and clinical ablation data.
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