Abstract #5438

Monitoring of Microbubbles Stable Cavitation in a Flowing Phantom by Using MRI

Cheng-Tao Ho¹, Chen-Hua Wu¹, Shih-Tsung Kang¹, Wen-Shiang Chen², Po-Hung Hsu³, Hao-Li Liu³, Chih-Kuang Yeh¹, and Hsu-Hsia Peng¹

¹Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, ²Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan, ³Department of Electrical Engineering, Chang-Gung University, Taoyuan, Taiwan

We aim to real-time monitor the signal intensity (SI) change of microbubbles in the presence of stable cavitation (SC) effect in a flowing phantom to comprehend the combining effects of SC and flow. Distinct reduced SI was observed, particularly in the focused ultrasound (FUS) focus and downstream regions, during transmitting FUS pulses. More substantial SI changes can be observed with increase of acoustic pressure. In this study, we verified the feasibility of using HASTE sequence to real-time monitor SI changes at the presence of SC effect of MBs in a flowing phantom.

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