Abstract #5439

PRF thermometry accuracy at 7.0T for thermal MR applications with and without the presence of fat

Michal Pham¹, Yiyi Ji¹, Hendrik Paysen¹, Eva Oberacker¹, Till Huelnhagen¹, Thoralf Niendorf^1,2,3, and Lukas Winter¹

¹Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, ²Experimental and Clinical Research Center (ECRC), a joint cooperation between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, Berlin, Germany, ³MRI.TOOLS GmbH, Berlin, Germany

Proton resonance frequency (PRF) shift temperature mapping is influenced by B₀ field drift, temperature dependent electromagnetic property changes that alter phase velocity, alpha calibration and temperature dependent magnetic susceptibility changes. This work details PRF thermometry at 7.0T of a thermal MR setup. In a homogeneous agarose phantom PRF reading accuracy is within the accuracy of fiber optic sensor readings (0.29±0.21)°C. Temperature dependent magnetic susceptibility changes in pure fat lead to significant temperature reading errors. However, for more realistic thermal MR applications in the human brain (ΔT<10°C, volume fat fractions <10-20%), temperature reading accuracy is comparable to water-based samples.

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