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Abstract #5472

Probing In Vivo Metabolite Relaxation by Linear Quantification of RF Driven Steady States

Linqing Li1, Ningzhi Li1, Li An1, and Jun Shen1

1National Institute of Mental Health, National Institute of Health, Bethesda, MD, United States

A driven steady states technique for brain metabolite relaxation measurement is proposed. Multiple steady states driven by long pulse train were used to quantify T2 of brain metabolites in vivo. The proposed technique does not need to vary echo time of the measuring sequence such as PRESS. A simple linear equation for quantification of driven steady state spectra was derived using Bloch equations. The derived equation was verified by Bloch simulations, phantom and in-vivo experiments.

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