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Abstract #5490

Improving the quality of DW spectra in the supraclavicular fossa with a navigator-gated and cardiac-triggered flow-compensated diffusion-weighted STEAM MRS acquisition

Dominik J. Weidlich1, Andreas Hock2, Stefan Ruschke1, Daniela Franz1, Hans Hauner3, Ernst J. Rummeny1, and Dimitrios C. Karampinos1

1Department of Diagnostic and Interventional Radiology, Technical University Munich, Munich, Germany, 2Philips Healthcare, Hamburg, Germany, 3Else Kröner Fresenius Center for Nutritional Medicine, Technical University Munich, Munich, Germany

Measuring in vivo blood perfusion within the brown adipose tissue depot of the human supraclavicular fossa is highly relevant in metabolic and obesity research. DW-MRS can probe perfusion properties by measuring the IVIM signal of the water peak. However, DW-MRS of the supraclavicular fossa remains a challenging task due the high sensitivity of the region to motion and the associated poor spectral quality. The present work proposes a DW-MRS methodology with a flow compensated acquisition combining cardiac and respiratory tracking to improve spectral quality. IVIM results for the water peak are shown for the first time in the supraclavicular fossa.

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