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Abstract #5504

Simultaneous water and lipid suppression for brain 1H MR spectroscopy at 7T using multiple RF pulses with spoiling phases

Linqing Li1, Li An1, Ningzhi Li1, and Jun Shen1

1National Institute of Mental Health, National Institute of Health, Bethesda, MD, United States

The variation of RF phases may effectively suppress water and lipid coherent signals, as similar effect has been previously demonstrated in GRE MR imaging sequences. We demonstrate a new suppression sequence capable of simultaneous water and lipid suppression with short inter-pulse delay and RF phase spoiling. Monte Carlo analysis showed that the proposed technique can significantly improve both accuracy and precision of metabolite quantification by suppressing lipid contamination.

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