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Abstract #5519

Covariance Five Dimensional Echo Planar J-resolved Spectroscopic Imaging

Zohaib Iqbal1 and M. Albert Thomas1

1Radiological Sciences, University of California - Los Angeles, Los Angeles, CA, United States

Chemical shift imaging is a very important method used to investigate several pathologies in vivo. A recent technological development incorporating an echo planar readout, a non-uniform sampling scheme, and an iterative, non-linear reconstruction is the five dimensional echo planar J-resolved spectroscopic imaging (5D EP-JRESI) method. While this technique is capable of obtaining 3 spatial and 2 spectral dimensions in vivo, the indirect spectral dimension has a low spectral resolution, which may hinder accurate metabolite quantitation. In this study, a novel approach using a covariance transformation after reconstruction is assessed and compared to the 5D EP-JRESI method.

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