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Abstract #5520

Comparison of different acceleration methods for high-resolution metabolite mapping using 1H FID MRSI at 9.4T

Sahar Nassirpour1,2, Paul Chang1,2, and Anke Henning1,3

1MPI for Biological Cybernetics, Tuebingen, Germany, 2IMPRS for Cognitive and Systems Neuroscience, Eberhard Karls University of Tübingen, Tuebingen, Germany, 3Institute of Physics, Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany

Reliable metabolite mapping of the human brain using ultra-short TE and TR 1H FID-MRSI is possible at ultra-high fields. However, MRSI studies with high spatial resolutions and brain coverage suffer from long scan times. To make these studies clinically relevant, different acceleration methods are used at the price of losing SNR. The aim of this study is to implement and compare different in-plane acceleration methods: SENSE, GRAPPA and compressed sensing for high-resolution metabolite mapping of the human brain at 9.4T without lipid suppression.

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